America's #1 instant hand sanitizer delivers advanced antimicrobial germ kill while being very kind to the skin. PURELL Advanced Instant Hand Sanitizer kills more than 99.99% of most common germs. This alcohol-based hand sanitizer works in as little as 15 seconds, with no water or towels needed. Provides unprecedented germ kill while soothing hands and maintaining skin health. PURELL Advanced is enhanced with four different skin conditioning agents that help maintain skin health—skin moisture and improves overall skin feel.